Brushing was performed in a toothbrushing machine (Pepsodent) with a soft brush and a suspension of toothpaste and distilled water for 300 minutes, representing 6 years of brushing. Weight was measured initially and after the trial period; roughness was measured after the trial period only. The results of roughness and weight loss were analyzed using ANOVA and Tukey

tests at 5%. Results: The negative control (2.82 ± 4.41 mg) showed the lowest weight loss. Experimental 1 (13.62 ± 4.29 mg) and Experimental 2 (15.4 ± 5.80 mg) were equal statistically, and Sorriso (23.22 ± 7.23 mg) and Corega (28.83 ± 6.34 mg) produced the greatest weight loss. Concerning roughness, the negative control group

(0.03 ± 0.01 μm) showed the lowest value. No significant differences were found between Corega (13.43 ± 1.65 μm), Experimental 1 (12.28 ± 0.85 μm), and PLX3397 in vivo Experimental 2 (10.68 ± 2.56 μm). The Sorriso toothpaste produced the greatest amount of surface roughness (19.15 ± 2.36 μm). Conclusion: Of the tested dentifrices, the experimental preparations proved to be the least abrasive and resulted in the lowest weight loss after brushing of the acrylic. Based on these findings, the use of these experimental dentifrices is advocated. Further evaluation based on the ability of these preparations to remove biofilms is learn more required. “
“Immediate load protocols for the edentulous mandible offer the patient 4-Aminobutyrate aminotransferase many advantages in terms of

decreased number of visits, improved early function, and reduction of surgical exposure; however, this treatment modality is not universally appropriate for all patients. The available evidence will assist the clinician in developing a customized and comprehensive informed consent. Patient selection and patient-mediated factors will dictate the suitability of not only a fixed or removable prosthesis, but also whether immediate loading would enhance the cost/benefit ratio. The indications, objective and subjective patient considerations, and design strategies are discussed for the immediate load scenario. “
“Purpose: Candida albicans is the predominant oral yeast associated with denture-induced stomatitis, and with an increasing population of denture wearers its incidence is increasing. Maintaining good oral and denture hygiene, through chemical and/or mechanical intervention, is essential to reducing this disease. The aim of this study, using a robust adherent C. albicans cell model system, was to evaluate and compare the efficacy of a novel denture cleanser to the efficacy of a commonly used dentifrice coupled with brushing. Materials and Methods: Four C.