His vital signs were within normal limit. He drug discovery had diffuse abdominal tenderness, especially in left upper quadrant and guarding. The laboratory findings were not significant. The CT showed 15 cm length intestinal wall

edematous enlargement at jejunum and high density area at mesentery around jejunum and ascites at Douglas cavum. He was radiologically diagnosed with small intestinal anisakiasis. It was resolved spontaneously in a few days. Conclusion: Discussion: Acute gastric anisakiasis can be easily diagnosed by the endoscopic visualization of Anisakis larvae along with mucosal edema, erythema, hemorrhage, and/or an ulcer. However, small intestinal anisakiasis Pexidartinib molecular weight is difficult to diagnose because we cannot endoscope it easily. The CT scan typically showed severe intestinal submucosal edema with ascites. The small intestinal anisakisis should be considered by the food history and the typical CT finding. If strongly suspected, small intestinal anisakaisis can be treated without surgery because the larvae will die within a few days and the symptoms will subside soon. Key Word(s): 1. Anisakiasis Presenting Author: OSAMU OGAWA Additional Authors: YUGO SUZUKI, AKIRA MATSUI, TOSHIFUMI MITANI, SHU HOTEYA, MITSURU

KAISE Corresponding Author: OSAMU OGAWA Affiliations: Toranomon Hospital, Toranomon Hospital, Toranomon Hospital, Toranomon Hospital, Toranomon Hospital Objective: Gastric adenocarcinoma of fundic grand type (GAFG) is neoplastic lesion mainly composed of highly differentiated columnar cells mimicking the fundic gland cells with nuclear atypia. It has been reported as a new, rare variant of gastric adenocarcinoma. Therefore, its endoscopic features are uncertain. The aim of the current study was to evaluate the endoscopic features of GAFG. Methods: From October 2012 to March 2013, three

consecutive patients with GAFG resected by endoscopic submucosal dissection (ESD) in our hospital were enrolled in this retrospective study. These specimens resected by ESD revealed well-differentiated adenocarcinoma mimicking fundic gland cells, which were positive for pepsinogen-1 GNAT2 (a marker of chief cells) and MUC6 (a marker of fundic gland cells). These findings were consistent with GAFG. To evaluate the endoscopic features of GAFG, they were examined for their location, background mucosa, shape, color, and size. Results: All three GAFGs were in the upper part of the stomach. In the background mucosa, all they had normal fundic gland mucosa without atrophic change. And all they had whitish submucosal tumor shape with dilated branching vessel, ranging in size from 5.0 to 6.0 mm (mean, 5.1 mm). Conclusion: Precise understanding of these endoscopic features must enhance efficacious detection of GAFG in endoscopic surveillance. Key Word(s): 1.