The questionnaire requested sociodemographic details, practice-related characteristics, and proposed three clinical situations with multiple choice questions (MCQ). To identify factors associated with a higher level of specific knowledge in travel medicine, results were studied by uni- and multivariate analyses. An overall score was calculated based on the MCQ answers and a motivation score was calculated based on parameters such as frequency and developments in pre-travel consulting at Rapamycin molecular weight the practice,

PCPs’ personal experience as travelers, and the formal agreement of PCPs to administer yellow fever vaccination. The response rate was 37.5%, with 150 questionnaires returned completed and suitable for analysis. After multivariate logistic regression, the three variables associated with a higher score were: proximity of a vaccination center (p = 0.001), motivation

score (p = 0.004), and absence of request for expert advice on malaria prophylaxis (p = 0.007). PCPs play an important role in travel medicine. This study showed that their high level of knowledge in travel medicine was mostly linked to their motivation to practice in this specialized discipline. Global international travel has increased considerably over the last few decades. The number of international travelers is roughly estimated at 900

million per year and should reach 1.6 billion per year in 2020.[1] Each BMS-354825 concentration year, 50 million people travel from industrialized countries to tropical areas. International travel from France mirrors this pattern, with around five million inhabitants visiting tropical areas each year.[1] Traveling abroad can lead to exposure to various diseases and following the expansion of international travel, primary care physicians (PCPs) are often consulted to provide medical pre-travel advice.[2] Travel next medicine is an emerging discipline born from the rising demand of the population but is not thoroughly studied by physicians. As the role of PCPs as first-line contacts for travelers seeking pre-travel advice has become increasingly significant, several worldwide surveys have investigated the quality of travel medicine practice among PCPs since 1987: four in the UK,[3-6] three in New Zealand,[7-9] two in Germany,[10, 11] one in America,[12] one in Qatar,[13] one in Australia,[14] and one in Switzerland.[11] In France, Bouldouyre et al.[15] recently published a survey focusing on the quality of pre-travel advice given by specialized physicians working in a travel medicine and vaccine center, but no study has yet focused on the quality of pre-travel advice given by French PCPs.