6, 137.6, 134.3, 134.1, 130.4, 130.2, 129.4, 129.1, 128.8, 128.2, 128.1, 126.7, 125.4, 123.2, 122.6, 115.3, 55.2 HRMS (EI) m/z calcd for C23H15ClN2O3S: 434.0492; found: 434.0488. This compound was prepared as per the above mentioned procedure purified and isolated as pale yellow solid: yield 72.6% mp 212 °C; IR (KBr) vmax 2950, 2840, 1718, 1290,747 cm−1; 1H NMR (CDCl3) δ ppm; 11 (s, 1H, COOH), 7.24–7.99 (m,11H, Ar–H), 2.47 (s, 3H, SCH3); 13C NMR (CDCl3) δ ppm; 168.4, 157.7, 144.6, 141.6, 139.6, 137.8, 134.4, 130.8, 130.4, 129.4, 129.2, 129.1, 128.7, 127.5, 127.3, 126.4, 124.2,
PR-171 purchase 122.6, 15.5; HRMS (EI) m/z calcd for C23H15ClN2O2S2: 450.0263; found: 450.0261. This compound was prepared as per the above mentioned procedure purified and isolated as dark yellow solid: yield 41.10% mp 201 °C; IR (KBr) vmax 2950, 2810, 1719, 1320, cm−1; 1H NMR (CDCl3) δ ppm; 11 (s, 1H, COOH), 7.24–8.10 (m, 11H, Ar–H), 3.79 (s, 3H, OCH3) 2.22 (s, 3H, CH3); 13C Ibrutinib cost NMR (CDCl3) δ ppm; 168.2,
162.6, 157.7, 144.2, 139.4, 137.4, 135.3, 133.4, 132.6, 130.2, 129.7, 129.4, 128.6, 126.6, 125.8, 123.6, 121.4, 115.6, 56.2, 22.3; HRMS (EI) m/z calcd for C24H18N2O3S: 414.1038; found: 414.1033. This compound was prepared as per the above mentioned procedure purified and isolated as slight yellowish solid: yield 83.55% mp 201 °C; IR (KBr) vmax 2950,2863, 1710, 1320, cm−1; 1H NMR (CDCl3) δ ppm; 11 (s, 1H, COOH), 7.10–8.10 (m, 11H, Ar–H), 3.90 (s, 6H, OCH3); 13C NMR (CDCl3) δ ppm; 169.2, 162.5, 157.7, 144.5, 139.6, 137.7, 132.5, 129.5, 128.5, 126.8, 125.2, 123.8, 122.4, 115.3, 56.5; HRMS (EI) m/z calcd for C24H18N2O4S: 430.4757; found: 430.4754. This compound
was prepared as per the above mentioned procedure purified and isolated as slight yellowish solid: yield 82.9% mp 203 °C; IR (KBr) very vmax 2950, 2715, 1714, 1220, 1140, cm−1; 1H NMR (CDCl3) δ ppm; 11 (s, 1H COOH), 7.36–8.10 (m, 11H, Ar–H), 2.99 (s, 3H, SCH3), 3.81 (s, 3H, OCH3); 13C NMR (CDCl3) δ ppm; 168.2, 162.7, 157.3, 144.2, 141.2, 139.6, 137.3, 132.5, 129.2, 128.8, 127.3, 127.1, 126.8, 123.6, 121.7, 115.3, 56.2, 15.8; HRMS (EI) m/z calcd for C24H18N2 O3 S2: 446.0759; found: 446.0754. This compound was prepared as per the above mentioned procedure purified and isolated as pale yellow solid: yield 66.3%; mp 210 °C; IR (KBr) vmax 2928, 2831, 1710, 1650, 1270, 740 cm−1; 1H NMR (CDCl3) δ ppm; 11 (s, 1H, COOH), 7.12–8.99 (m, 10H, Ar–H), 2.65 (s, 3H, CH3); 13C NMR (CDCl3) δ ppm; 168.2, 157.2, 144.6, 139.7, 137.7, 137.0, 135.5, 131.7, 130.2, 130.0, 129.3, 129.1, 128.4, 127.7, 126.8, 125.2, 124.2, 122.4, 22.4; HRMS (EI) m/z calcd for C23H14Cl2N2O2S: 452.0153; found: 452.0150.