, 2006, Aguiar and Maugeri, 2010 and Alvarado-Huallanco and Maugeri, 2010). A typical composition of the reaction mixture is: 65 g/100 g FOS, 25 g/100 g glucose, 5 g/100 g fructose, and 5 g/100 g sucrose (Aguiar and Maugeri, 2010, Alvarado-Huallanco

and Maugeri, 2010 and Sangeetha et al., 2004). Nizhizawa, Nakajima, & Nabetani (2001) proposed to increase the content of FOS by Afatinib mw simultaneous removal of glucose via an enzymatic reaction, since glucose is an inhibitor of the enzymatic reaction at concentrations higher than 10–15 g/100 g. However, the results from this study have shown another possibility to increase the yield of FOS in the reaction media. The zeolite NaX was shown to be selective for glucose and fructose, since about 20 g/100 g of the initial concentration was recovered after 60 min of reaction, while for FOS and sucrose a very low adsorption was detected. Therefore, this

zeolite type can be used in situ to remove the excess of glucose during the enzymatic reaction of FOS production. This strategy will allow the use of high initial concentration of sucrose, compensating the amount of fructose that will bind to the zeolite, increasing the FOS yield. In this work, single component adsorption Daporinad ic50 of glucose, fructose, sucrose and fructooligosaccharides using six cationic forms (Na+, Ca+2, Ba+2, Sr2+, K+ and Mg2+) of the X zeolite was investigated in stirred tank reactor. A mathematical model was proposed taking into account the kinetic and mass transfer phenomena. Based on the experimental results, the most appropriated form to separate glucose, fructose Nintedanib (BIBF 1120) and sucrose from the reaction medium was determined, which are the adsorbent in the forms NaX, NaX or BaX and MgX or CaX, respectively. The FOS adsorption kinetics was performed using

the NaX zeolite, so that a low adsorption capacity and a higher mass transfer resistance were found, which resulted in a low efficiency separation. The analysis over the estimated parameters and experimental led to a conclusion that the NaX zeolite was the most appropriated adsorber, since it showed higher adsorption rates and, mainly, lower mass transfer resistance than any other cationic forms. The strategy adopted to select the adsorbent material was shown to be interesting and applicable for the selection of any other adsorbent material for the separation of bioproducts of interest, since the criterion is based on experimental data, adsorption rates and mass transfer phenomena. The authors are grateful to CNPq for the financial support and scholarship. “
“Polycystic ovary syndrome (PCOS) is a common endocrine disorder, affecting 5% to 10% of women of reproductive age. It is a major cause of anovulatory infertility, irregular menstrual cycles, and hirsutism [1], [2], [3], [4], [5] and [6]. Obesity is present in 30% to 75% of women with PCOS.