Surgical choice for 3rd ventricle tumors needs meticulous planning, because of the complex anatomic milieu. Traditional available microsurgical approaches are restricted within their access to particular tumors, prompting the research of alternative techniques. The endoscopic supraorbital translaminar strategy (ESOTLA) features emerged as a promising substitute for managing these tumors. By combining a minimally invasive keyhole approach with endoscopic visualization, the ESOTLA provides improved lighting and a wider direction of view within the 3rd ventricle. This excellent advantage enables Stenoparib mw for improved access to retrochiasmatic tumors and reduces the necessity for front lobe and optic chiasm retraction needed of microscopic techniques, decreasing the possibility of neurocognitive and aesthetic deficits. Complications regarding the ESOTLA tend to be rare and primarily pertain to aesthetic problems and potential compromise for the hypothalamus or optic equipment, that can easily be minimized through mindful subarachnoid dissection. This chapter provides a thorough description of this technical aspects of the ESOTLA, offering insights into its application, advantages, and prospective limits. Also, an instance information highlights the successful surgical extirpation of an intraventricular papillary craniopharyngioma via the ESOTLA accompanied by specific therapy. To better show the stepwise dissection through this novel approach, a few cadaveric and intraoperative photographs are included. Considerable energy is built to reduce medical invasiveness, since Axel Perneczky introduced the supraorbital eyebrow approach as a core part of their keyhole idea in neurosurgery. But a restricted method will not facilitate an already serious and demanding task as aneurysm surgery. In this respect, the enhancement associated with the visual area before, during, and after microsurgical aneurysm occlusion is a secure and efficient approach to boost the quality of treatment. Indications/Contraindications on the basis of the specific anatomical conclusions, the supraorbital keyhole approach provides access to many aneurysms of this anterior blood circulation. The approach just isn’t recommended in large Vacuum Systems complex aneurysms, giant aneurysms, BA aneurysms found beneath the dorsum sellae, in addition to situations of extreme subarachnoid hemorrhage (SAH) and expected mind edema. Knowledge about endoscopic treatments in aneurysm surgery is bound immunological ageing to many clinical retrospective articles, and no major problems with the endoscof most aneurysms of the anterior blood supply. The additional improvement associated with the visual field provided by the endoscope before, during, and after microsurgical aneurysm clipping might decrease the rate of intraoperative aneurysm ruptures and unanticipated findings concerning aneurysm remnant occlusion and compromise of involved parent, branching, and perforating vessels. Anterior cranial base meningiomas consist of those meningiomas originating through the tuberculum sellae, the planum sphenoidale, or perhaps the olfactory groove, with medical excision being the key therapy modality for these tumors. Mainstream minute and endoscope-assisted versions of the supraorbital keyhole approach via an eyebrow cut surfaced into minimally unpleasant options which can be regularly used today for treating these tumors. In the early attempts of endoscope-assisted cranial surgery, it had been noted that rigid endoscopes enabled overcoming the problem of suboptimal visualization when small exposures are used. The technical specifications and design of this currently available rigid endoscopes are related to a team of unique features that define the endoscopic view and put the basis for its superiority on the microscopic view during mind surgery. Notwithstanding, the totally endoscopic or endoscope-controlled form of the supraorbital keyhole approach is not routinely practiced by neual treatments. Within our arms, the strategy seems to be possible, efficient, and minimally unpleasant with positive results. Tumors associated with skull base could be accessed through various routes. Recent advantages in minimally unpleasant techniques have shown that really different roads is sent applications for optimal tumor resection depending on the technical gear, the surgeon’s inclination, in addition to specific anatomy for the pathology. Here, the writers present their way of pure endoscopic transcranial cyst resection in meningiomas. Out of the situations for the Department of Neurosurgery, Homburg Saar Germany of the last a decade, all endoscopic processes for meningiomas were examined. Specific attention was presented with to assessing the peculiarities of the meningiomas that have been treated strictly endoscopically. Whilst the endoscope was found in a large number of skull base meningiomas in endonasal approaches or for endoscopic evaluation in transcranial skull base surgery, just a small amount of meningiomas ended up being chosen for a purely endoscopically performed resection. The qualities among these situations were rather a little lesion, strathe keyhole approach are good applicants for pure endoscopic resection. Because of the high magnification while the minimally invasive nature for this approach, it should be considered more frequently in appropriate lesions.Cerebral hemorrhage is a frequent disease and one of this primary factors behind handicaps.