According to Mj?r22 and Saleh,23 development of secondary caries is not only due to the selleck catalog material itself. Clinical environment, caries experience of patients, criteria for replacements, different handling characteristics appeared to affect clinical results. Additionally, Bernardo et al24 reported that the overall risk of failure due to secondary caries was 3.5 times higher in composite restorations than in amalgam restorations. Grandio restorations have already showed 10% Bravo scores in terms of marginal adaptation, which is statistically significant between baseline and 12 months. Similar to our results, Kramer et al5 found that for marginal adaptation Grandio showed 17% Bravo scores after one year clinical evaluation period.

However, previous researches demonstrated that evaluation of the composites during initial periods of evaluation depicted minor changes compared to the baseline.25,26 Marginal adaptation is directly influenced by the type of composite resin used.27 Altering the amount and quality of the filler particles can change the esthetics and mechanical properties of restorative composite resins. Furthermore, lowering a material��s viscosity by modifying the composition of the monomer system permits a higher filler load and at the same time improves the handling properties. 28 Grandio has a filler degree of 87% w/w (71% volume) by combining spherical nano particles and none of the restorations had shown any marginal discoloration and anatomic form loss until the end of the 12 months and no restorations exhibited post-operative sensitivity at any evaluation period.

Quixfil has 86% by weight (66% volume) filler load, which is approximately the same. In a previous study, Manhart et al29 evaluated the clinical performance of Quixfil for 18 months and found significant increase in marginal discoloration with time. While, marginal defects were observed for both materials in our study, none of the restorations showed marginal discoloration. Many of the these marginal defects appeared to result from the fracture of thin flashes of resin composite material extended on non-instrumented enamel surfaces adjacent to the cavity margins. The use of phosphoric acid etching30 and aggressive self-etch adhesives32 may reduce the occurrence of such defects, especially in high-stress-bearing areas, because of the improved enamel etching.

30 In the present study, mild self-etch adhesive systems were used and marginal adaptation results for 12 months may be related to absence of acid-etching procedure. In consistent to our results, Drug_discovery Abdalla and Garcia-Godoy31 evaluated the clinical performance of FuturaBond NR in class V lesions and reported less deteriorations in regards to marginal adaptation and marginal discoloration when adhesive resin was applied following enamel etching. In the present study, both of the restorative materials demonstrated good color stability and surface texture.