Joint British Association of Dermatologists, UK Cutaneous Lymphom

Joint British Association of Dermatologists, UK Cutaneous Lymphoma Group guidelines for the management of primary cutaneous T-cell lymphomas. Br J Dermatol 2003; 149: 1095–1107. 109 Willemze R, Dreyling M; ESMO Guidelines Working Group. Primary cutaneous lymphoma: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 2009; 20(Suppl 4): 115–118. 110 Bunker CB, Neill SA. The genital, perianal and umbilical regions. In: Burns T , Breathnach S , Cox N and Griffiths

C (eds). Rook’s Textbook of Dermatology. 8th edn. Wiley-Blackwell, New York; 2010. 111 Porter, WM, Francis N, Hawkins D, Dinneen M, Bunker CB. Penile intraepithelial neoplasia: clinical spectrum and treatment of 35 cases. Br J Dermatol 2002; 147: 1159–1165. 112 Shim TN, Hawkins D, Muneer A et al. Male genital FK228 cost dermatoses in immunocompromised patients. Br J Dermatol 2013; 169 (Suppl 1): 99. 113 Shim TN, Hawkins D, Muneer A et al. Male genital dermatoses in HIV. Sex Transm Infect 2013; 89(Suppl 1): A1–A428. 114 Evans

MW, Sung AD, Gojo I et al. Risk assessment in human immunodeficiency virus-associated acute myeloid leukemia. Leuk Lymphoma 2012; 53: 660–664. 115 Sanfilippo NJ, Mitchell J, Grew D, DeLacure M. Toxicity of head-and-neck radiation therapy in human immunodeficiency virus-positive patients. Int J Radiat Oncol Biol Phys 2010; 77: 1375–1379. 116 Klein EA, Guiou M, Farwell DG et al. Primary radiation therapy for head-and-neck cancer in the setting of human immunodeficiency virus. Int J Radiat Oncol Biol Phys 2011; 79: 60–64. 117 Goedert JJ, Schairer C, McNeel TS et al. Risk of breast, ovary, and uterine corpus cancers among 85,268 women with AIDS. Br J Cancer 2006; 95: 642–648. 118 Shiels MS, Goedert JJ, Moore RD et al. Reduced risk of prostate cancer in U.S. men with AIDS. Cancer Epidemiol Biomarkers

Prev 2010; 19: 2910–2915. 119 Kahn S, Jani A, Edelman S et al. Matched cohort analysis of outcomes of definitive radiotherapy for prostate cancer in human immunodeficiency virus-positive patients. Int J Radiat Oncol Biol Phys 2012; 83: 16–21. 120 Pantanowitz L, Bohac G, Cooley TP et al. Human immunodeficiency virus-associated prostate cancer: clinicopathological findings and outcome in a multi-institutional study. BJU Int 2008; 101: 1519–1523. HIV infection causes immunosuppression, CD4 lymphocyte count loss and a progressive risk of opportunistic infection Farnesyltransferase and tumours. Similarly chemotherapy and radiotherapy for HIV-related malignancies is associated with an increased risk of infection secondary to the myelosuppression and additional CD4 lymphocyte count loss [1–3]. The risk of infection is further raised by the presence of central venous catheters [4–7], neutropenia associated with HIV infection [8,9] and many of the therapies utilized to treat HIV and its complications [10–12].These factors all combine to produce a significant risk of opportunistic infection in people living with HIV who are undergoing treatment for cancer.

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