Procedures-Medical records were evaluated for information
on signalment; history; physical examination, diagnostic imaging, surgical, histologic, and necropsy findings; and outcome.
Results-Ten cats were < 1 year old, and 9 were >= 6 years old. Anorexia (14/17), lethargy (12/17), and vomiting OSI-906 cost (12/17) were the most common reasons for examination. Dehydration (13/18), poor body condition (12/18), signs of abdominal pain (8/18), and an abdominal mass (8/18) were the most common physical examination findings. Abdominal radiography revealed intestinal obstruction in all 10 cats in which it was performed; abdominal ultrasonography revealed intussusception in all 7 cats in which it was performed. The most common intussusception was jejuno-jejunal (8/20), and no intussusceptions were found proximal to the duodenum. Eleven of 13 cats that underwent GSK2879552 research buy laparotomy required intestinal resection and anastomosis. Histologic examination revealed intestinal lymphoma or inflammatory bowel disease in 7 of 8 cats >= 6 years old and idiopathic intussusception in 7 of 8 cats
< 1 year old.
Conclusions and Clinical Relevance-Results suggested that in cats, intussusception has a bimodal age distribution, is most commonly jejuno-jejunal, often requires surgical resection and anastomosis, is often associated with alimentary lymphoma or inflammatory bowel disease in older cats, and is readily diagnosed by means of ultrasonography. (J Am Vet Med Assoc 2009; 234: 771-776)”
“Background:
Disordered metabolism of phosphorus is one of the hallmarks of chronic kidney disease (CKD), resulting in increased cardiovascular morbidity and mortality. Age and sex may affect the metabolism of phosphorus and subsequently its serum level. We evaluated if age-and sex-specific cutoffs for hyper-phosphatemia may define cardiovascular risk better than the current guideline cutoffs.
Methods: We used data from 16,834 subjects participating in the 1999-2006 National Health and Nutrition Examination Survey (NHANES); the prevalence of self-reported cardiovascular disease (CVD) and mortality selleck chemicals llc rates were analyzed in CKD patients for both the classic definitions (CH; i.e., NKF-KDOQI and K-DIGO) and a tailored definition (TH) of hyperphosphatemia by means of regression models adjusted for age, sex, race/ethnicity, smoking status and body mass index. The cutoffs for TH were represented by the 95th percentile of an age-and sex-matched non-CKD population.
Results: Serum phosphorus levels showed an inverse correlation with age (r=-0.12; p<0.001); females showed higher levels than males (3.78 +/- 0.54 mg/dL vs. 3.62 +/- 0.58 mg/dL; p<0.001). Even if the association between the TH definition and CVD was marginally better compared with the CH definition (odds ratio [OR] = 1.49, 95% confidence interval [95% CI], 1.04-2.13; p=0.030 vs. OR=1.55, 95% CI, 0.98-2.44; p=0.059), the TH model was not superior in predicting CVD or mortality.