The model is validated using experimental data. Extensive simulations are performed to study the complicated interactions between multi-physics transport processes and chemical/electrochemical reactions. The results elucidate the fundamental mechanisms of direct H2S
fueled SOFCs. It is found that suitably increasing the H2O content in the supplied H2S fuel can improve SOFC electrochemical performance; high operating temperature may facilitate the reforming of H2S and improve the electrochemical buy PD173074 performance. The sulfur poisoning effect may be mitigated by increasing the H2O content in the fuel, increasing the operating temperature, decreasing the flow rate, and/or making the cell work at low voltage (or high current) conditions.”
“In mammalian cell culture, single-use bioreactors are widely used. Different hardware designs are available, ranging from stirred tank reactors to wave GSK2399872A manufacturer mixed and cubical shaken systems. Unlike in stainless steel systems, where standards exist, in single-use bioreactors aeration devices are often predefined by the supplier. While ring sparger systems are the gold standard in stainless steel bioreactors, not all single-use bioreactors are available with ring spargers. In this study, a comprehensive characterization of two stirred tank single-use bioreactor systems (XDR (TM) from
Xcellerex and S.U.B. from Thermo Scientific Hyclone) was performed under GMP conditions with 200/250 L and 1000 L bioreactors. Engineering facts like mass transfer rates for oxygen k(L)a(o2) and carbon dioxide k(L)aCO(2) as well as mixing number were evaluated. To achieve improved similarity VEGFR inhibitor in key engineering parameters and in consequence cell culture performance, the submerse aeration device of the S.U.B. (to date only open tube and frit) was remodeled resulting in a drilled hole sparger design. Results of the characterization showed that k(L)a(o2) in the S.U.B. was enhanced from 8.5 h(-1) to 11.5 h(-1) at the maximum, and the k(L)aCO(2) was very similar between both bioreactor types. Knowledge of the characterization data as well as improved
oxygen transfer rate in the S.U.B. allows for an interchangeable usage of the two different single-use bioreactors.”
“Context: Children with calcium-deficiency rickets have high 1,25-dihydroxyvitamin D values.\n\nObjective: The objective of the study was to determine whether vitamin D increased calcium absorption.\n\nDesign: This was an experimental study.\n\nSetting: The study was conducted at a teaching hospital.\n\nParticipants: Participants included 17 children with nutritional rickets.\n\nIntervention: The participants were randomized to 1.25 mg oral vitamin D-3 (n = 8) or vitamin D-2 (n = 9).\n\nMain Outcome Measure: Fractional calcium absorption 3 da after vitamin D administration was measured.\n\nResults: Mean baseline 25-hydroxyvitamin D concentrations were 20 ng/ml (range 5-31 ng/ml).