The characteristics of the 60,393 women who participated in GLOW are displayed in Table 4. The mean age was 69 years and mean weight 148 lb (67.2 kg). Among characteristics known to place women at increased risk of fragility fracture, weight <125 lb (57 kg) was present in 16%,

history of maternal hip fracture in 13%, and personal history of a fracture of the wrist, spine, or hip in 12%. Twenty-two percent had been told by a AZD1152 doctor or health professional that they had osteoporosis; 11% reported asthma, and 11% rheumatoid arthritis; 23% of women said their health status was “fair” or “poor.” Table 4 Characteristics of women participating in GLOW, US women participating in GLOW, and NHANES women aged 55 years and older for 2005 to

2006   All GLOW women US GLOW womena NHANES women (2005–2006) (n = 60,393) (n = 28,170) Mean age, years (SE) 69 (0.04) 69 (0.05) 68 (0.32) Mean weight, lb (SE) 148 (0.3) 159 (0.2) 163 (1.0) % Weight < 125 lb (57 kg) 16 15 16 Broken wristb 8.7 7.4 9.8c Broken spineb 2.3 1.9 1.6c Broken hipb 1.9 2.1 2.1c Maternal hip fracture 13 13 11c Ever diagnosed with Asthma 11 14 12 Chronic bronchitis or emphysema 9 9.1 12 High cholesterol 50 57 54 Hypertension 51 56 56 Osteoporosis 22 20 24c Osteoarthritis or degenerative joint disease 40 32 24 Rheumatoid arthritis 11 9.4 8.5 General health “fair or poor” 23 15 22 Non-Hispanic white NA 86 80 Education level Less than high school NA 7.4 23 High school NA 26 30 More than high school selleckchem NA 67 47 NA not available, SE standard error aFrequencies are age-standardized to the whole GLOW population bFractures are

since age 45 in GLOW, “ever” in NHANES cData are from NHANES 2003 to 2004 (n = 1,108), the latest year with these data available Comparisons of demographic characteristics and risk factors for the US GLOW Trichostatin A cost subjects and for women aged 55 and older sampled in the NHANES study (2005 to 2006) are also displayed in Table 4. Although the mean ages for the two groups were similar, women Cyclin-dependent kinase 3 in the GLOW sample had received a higher level of education, were more often white, and had better self-reported health than women in the NHANES study. History of wrist fracture was also somewhat lower in the GLOW population than in the NHANES population. However, many of the risk factors were similar among the two samples, for example low weight, osteoporosis diagnosis, fracture of the spine or hip, and maternal fracture. The prevalence of common comorbid conditions, such as hypertension, high cholesterol, and asthma, was also similar. When women were asked how concerned they were about osteoporosis, 54% expressed “some” concern and 25% said they were “very concerned” about the condition (Table 5).